Intrauterine insemination (IUI) is a type of artificial insemination procedure. The
fertility experts perform IUI when females cannot conceive with traditional methods.
During the IUI treatment, doctors push the concentrated sperm into the uterus.
Embryologists carry out this procedure when the ovary releases one or more eggs to
ensure fertilization. The implanted sperms swim across the fallopian tube and fertilize
the egg, leading to the pregnancy. Depending on the condition of your body, a fertility
doctor can prescribe IUI treatment with or without fertility medicines.
Indication of (IUI)
Intrauterine insemination can be a process of choice for couples with:Unexplained
infertility: If the reason for infertility is unknown, your fertility doctor may often
recommend IUI as a first treatment.Donor sperm: Sometimes, women may need donor sperm to
achieve pregnancy. In such cases, IUI can be a process of choice. You may get frozen
donor sperms specimens from certified labs.Male infertility: Sometimes, male partners
may have below-average sperm concentration, defective sperm motility, or any other
abnormality in size and shape of sperm. IUI can be a choice in such cases, as IUI
separates healthy and motile sperms from the lower-quality ones.Endometriosis-related
infertility: Endometriosis is a disorder in which tissue lining the uterus wall grows
outside the uterus. In endometriosis, this tissue growth can be on the ovaries,
fallopian tubes, or sometimes, even the intestines. For Endometriosis-related
infertility, your doctor may recommend IUI along with prescribing medicines to obtain a
good-quality egg.Cervical infertility: The cervix is an opening between the vagina and
uterus. During ovulation, mucus produced by your cervix helps in the sperms’ movements
from the vagina to the fallopian tubes. Any abnormal thickening of this mucus may impede
this journey of sperms. Even abnormal thickening of the cervix (caused by scarring due
to biopsy or procedures) is a barrier between sperm and the egg. During IUI, the doctor
put sperms directly into the uterus, thus eliminating the need for an ideal cervical
environment.Infertility due to problems in ovulation: Some females may experience
infertility due to problems with ovulation, such as the absence of ovulation or
ovulation with a reduced number of eggs. IUI may be a procedure of choice in such cases
Intrauterine insemination is a safe procedure. The probability of any complication
related to IUI treatment is low. Some risks associated with IUI include
Multiple pregnancies: IUI with ovulation-inducing medications increases the risk of
Various stages of IUI
Preparation of semen:
The non-sperm elements in your partner’s semen may interfere with fertilization. The
sample preparation includes the separation of highly active and healthy sperms from
lower-quality sperm and other non-essential elements to increase the likelihood of
Ovulation is the most critical factor for the success of IUI. Your doctor will monitor
for signs of impending ovulation. The doctor may visualize your ovaries and egg growth
through imaging techniques. You may get an injection of human chorionic gonadotropin
(HCG) or other medicines for ovulation at the right time.
During the procedure:
The intrauterine insemination procedure usually takes about 15 to 20 minutes. This
procedure may not require the use of any pain killer.
Your doctor inserts a speculum into the vagina.
The doctor inserts a catheter into the vagina. Your fertility expert pushes healthy
sperm into the uterus through the catheter.
The doctor may keep you under observation for some time. You can resume daily activities
immediately after the procedure.
What to expect after Intrauterine insemination?
After two weeks, you can carry out the at-home pregnancy test. If the test is positive,
your doctor may prescribe a blood test to confirm the pregnancy.